Insulin binding, insulin degradation and glucose metabolism in human monocytes
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چکیده
منابع مشابه
Oral glucose tolerance test,blood insulin level and lipids metabolism in women with idiopathic hirsutism
It is becoming apparent that is patients with hirsutism, metabolic aberrations are of greater health importance rather than unwanted hair growth.in this respect , evaluation of carbohydrate and lipid metabolism was carried out on a group of 92 women with idiopathic hirsutism(IH).these were divided into: obese and non-profit obese groups.seventy healthy subjects were also taken as control group...
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Insulin binding to monocytes and insulin action in vivo was examined in 14 obese subjects during the postabsorptive state and after starvation and refeeding. Tissue sensitivity to insulin was evaluated with the euglycemic insulin clamp technique. The plasma insulin concentration is acutely raised and maintained 100 muU/ml above the fasting level, and plasma glucose is held constant by a variabl...
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4 LIST OF PAPERS 5 ABBREVIATIONS 6 INTRODUCTION 7 Insulin resistance 8 The role of insulin in glucose and lipid turnover 8 Insulin signalling 10 Cellular glucose transport 13 Cellular insulin resistance 14 Lipid metabolism and the adipose tissue in insulin resistance 16 Human insulin resistance and type 2 diabetes 18 Neuroendocrine and humoral factors causing insulin resistance in vivo 19 AIMS ...
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*Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115; ‡Howard Hughes Medical Institute, Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037; Departments of §Biology and ¶Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093; Labo...
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The effect of chronic physiologic hyperglucagonemia on basal and insulin-mediated glucose metabolism was evaluated in normal subjects, using the euglycemic insulin clamp technique (+50, +100, and +500 microU/ml). After glucagon infusion fasting glucose increased from 76 +/- 4 to 93 +/- 2 mg/dl and hepatic glucose production (HGP) rose from 1.96 +/- 0.08 to 2.25 +/- 0.08 mg/kg X min (P less than...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1979
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf01222206